The actor said he was surprised by the poor quality of the film, which also starred Billy Bob Thornton and Susan Sarandon.
He said, "Man, that movie was so bad. I managed to watch about 15 minutes of it before I gave up.
"Billy Bob Thornton didn't ever watch it. It was really a case of that movie not being what it could have been and I'm sorry."
"You know, my friends back in Minnesota are proud of me, but they're not afraid to tell me when I've done a crappy film like that one, or The Dukes of Hazzard."
Scott admits that he is still struggling to overcome being typecast by his character Scott Stifler in the American Pie franchise.
"On the one hand, [Stifler] created a real career for me," he said. "It gave me the opportunity to take care of my family. But it really is this one-dimensional, over-the-top, silly, stupid character."