The film follows gameshow-obsessed Anne (Awkwafina) and her train wreck of a sister, Jenny (Oh) as they work together to try to cover their mother's gambling debts.
After Anne's dog is kidnapped, the pair set out on a cross-country trek to try to get their hands on some cash the only way they know how - by helping Anne to become a gameshow champion.
Quiz Lady is set to hit the streaming platform on November 3.
The movie also stars Jason Schwartzman, Holland Taylor, Tony Hale, and Will Ferrell.
Oh and Awkwafina are both onboard as producers, as are Ferrell, D'Angelo and Jessica Elbaum, Maggie Haskins, and Itay Reiss.
Awkwafina recently voiced Scuttle in Disney's live-action The Little Mermaid and is co-creator, writer and executive producer for TV show Awkwafina Is Nora from Queens.
Oh, who had a long-running role in Grey's Anatomy, has multiple projects in the works, including returning to voice Debbie Grayson in the animated adult superhero series Invincible and a role alongside Julianne Moore in Stone Mattress.
Could she even reprise her Princess Diaries role of Geraldine Gupta?
Quiz Lady lands on Disney + on November 3.
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