In the 1989 romantic comedy, Meg Ryan’s character Sally fakes an orgasm in the middle of a New York deli.
Reid did the impression in response to a Radio 4 interview with Oxford professor John Bell, which made headlines when he responded “yes, yes, yes” to the question of whether a new coronavirus vaccine could mean normal life will resume next spring.
Sitting alongside her co-host Piers Morgan, Reid did her best Ryan voice as she cried: “Yes, yes, yes!”
Watch: This former Love Island contestant claims she has never had an orgasm
“Blimey,” Morgan replied, as Reid laughed and added: “This is Pfizer – the company behind the vaccine which also created Viagra. So you know, it all comes together.”
On Monday (9 November) scientists hailed a major breakthrough in the fight against Covid-19 after Pfizer and its German partner BioNTech announced that their vaccine appears to be 90 per cent effective in preventing disease, in what has been described as “a great day for science and humanity”.