The action revolves around a woman who is forced to choose between the husband she's long believed to be dead and the fiancé responsible for bringing her back to life.
She's the Man director Andy Fickman is scheduled to roll cameras later this year in Massachusetts.
Earlier this week, actor Liu expressed his delight over joining the project, tweeting: "ASIAN. ROMANTIC. LEADS! There's nothing quite like the feeling of turning a character Asian.
"It's more than a face; it's about painting all of this new form with exciting colours, from all his experiences to his insecurities. I can't wait to show you."
Meanwhile, Liu recently directed criticism towards his sitcom Kim's Convenience, which he considered lacking in diversity behind the scenes.
"Aside from [creator Ins Choi], there were no other Korean voices in the [writers] room," he wrote.
"I voiced my interest in shadowing a director or writers' room... my prior experience had taught me that if I just put myself out there enough, people would be naturally inclined to help. And boy was I wrong here."
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