Also returning from the original cast is Doug Jones as Billy Butcherson.
As for new additions, the sequel is bringing some star-studded names to Salem, including Game of Thrones' Hannah Waddingham (who recently brought home an Emmy for her role in Ted Lasso), Arrested Development's Tony Hale and Veep's Sam Richardson.
While it's still unclear what roles Waddingham and Richardson will play, Hale will reportedly portray the mayor of Salem.
Taking on the protagonist roles are Whitney Peak (Gossip Girl) as Becca, Lilia Buckingham (Crown Lake) as Cassie, and Belissa Escobedo (American Horror Stories) as Izzy, three girls in present-day Salem who incite the wrath of the witches trio.
"It’s been 29 years since someone lit the Black Flame Candle and resurrected the 17th-century sisters who were executed for practising witchcraft, and they are looking for revenge," read the official description of the movie.
"Now it is up to three high-school students to figure out how to stop the ravenous witches from wreaking a new kind of havoc on Salem before midnight on All Hallow’s Eve."
Rounding out the cast are Juju Brener, Froy Gutierrez, Taylor Page Henderson and Nina Kitchen.
The film, which will premiere autumn 2022 on Disney+, is currently in production in Rhode Island.
“I am beyond thrilled to be involved in the sequel to a film that is as beloved as Hocus Pocus,’” said director Anne Fletcher.
“Fans around the world have embraced these characters and have made this film a Halloween tradition whose popularity continues to grow, and how lucky am I to be back at Disney with these three extraordinarily talented ladies in the iconic roles they created, as well as our fabulous new additions to the cast?”
Watch: Hocus Pocus cast: Then v Now